Marine-derived Trichoderma Species as a Promising Source of Bioactive Secondary Metabolites

Author(s): Dengquan Su , Lijian Ding* , Shan He* .

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 18 , Issue 20 , 2018

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Graphical Abstract:


Marine-derived fungi Trichoderma genus are serving as a valuable resource for structurally novel natural products encompassing a variety of chemical substances and diverse pharmacological applications. So far, about 78 metabolites have been structurally documented from the species of marine Trichoderma genus and a large proportion of these metabolites exhibited therapeutic properties with potential application in drug discovery. This mini-review focuses on the structures and bioactivities of these secondary metabolites from marine-derived Trichoderma species.

Keywords: Secondary metabolites, marine fungi, Trichoderma, bioactivity, Aspergillus, alkaloids.

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Article Details

Year: 2018
Page: [1702 - 1713]
Pages: 12
DOI: 10.2174/1389557518666180727130826
Price: $58

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