Recent Advances of Water-Soluble Fullerene Derivatives in Biomedical Applications

Author(s): Xiaoyan Zhang, Hailin Cong*, Bing Yu, Qun Chen.

Journal Name: Mini-Reviews in Organic Chemistry

Volume 16 , Issue 1 , 2019

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Abstract:

Fullerenes, especially C60, exhibit great potential applications in biology field, due to their excellent antibacterial, antiviral, antitumor and other properties. Many water-soluble fullerene derivatives have been designed, synthesized and used as photo-dynamic therapy agents, antiviral agents, bioimaging agents, drug carriers and so on. This review focuses on the usage of water-soluble fullerene derivatives in biomedical field in recent years. The first half gives the preparation of water-soluble fullerene derivatives themselves with covalent bonds and non-covalent bonds. In the second half, myriad applications of water-soluble fullerene derivatives in biomedical field are introduced.

Keywords: Fullerenes, fullerenol, water-soluble, biomedical, photo-dynamic therapy agents, sugar.

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Article Details

VOLUME: 16
ISSUE: 1
Year: 2019
Page: [92 - 99]
Pages: 8
DOI: 10.2174/1570193X15666180712114405
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