Background: Medicinal plants are rich source of large variety of lead compounds. The
plants of genus Glycosmis or its different parts valued for its therapeutic and medicinal qualities.
Glycosmis belongs to the family Rutaceae.
Objective: The genus Glycosmis is a rich source of pharmacologically and biologically active secondary
metabolites, such as alkaloids, flavonoids, phenolic glycosides, quinones, terpenoids, glycerides
isolated from different parts of Glycosmis plant. The objectives of this review is to provide updatedand
complete information on the distribution, phytochemical, pharmacological, and toxicity research
of Glycosmis species.
Results: About 233 phytoconstituents are isolated from this genus. Recent interest in this genus has
focused on isolating and identifying of different phytoconstituents that exhibit potent antioxidant,
antibacterial, antiviral and anticancer activities. They show good cytotoxic activity against various
cancer cell lines and also reported for good antiviral and immunomodulatory activity. In this support
convincing evidence in experimental animal models are available.
Conclusion: This review summarizes information about the isolated compounds their bioactivities
related to same compounds present in other plants including pharmacological activities of plant extract
of Glycosmis genus.