Research and Development of Proteins and Peptides with Therapeutic Potential from Yam Tubers

Author(s): Liang Zhang, Tzi Bun Ng, Jenny Ka Wing Lam, Shi Wei Wang, Lixing Lao, Kalin Yanbo Zhang, Stephen Cho Wing Sze*.

Journal Name: Current Protein & Peptide Science

Volume 20 , Issue 3 , 2019

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Abstract:

We discuss the diverse biological activities, therapeutic potential, and clinical applications of peptides and proteins isolated from various yams species including Dioscorea opposita Thunb (Chinese yam), D alata, D japonica (Japanese yam), D pseudojaponica, D batatas (Korea yam), and D cayenensis. Yam peptides and proteins have many pharmacological activities including immunomodulatory, antioxidant, estrogen-stimulating, osteogenic, angiotensin I-converting enzyme inhibiting, carbonic anhydrase and trypsin inhibiting, chitinase, anti-insect, anti-dust mite, lectin, and anti-proliferative activities. Yam peptides and proteins have therapeutic potential for treating cardiovascular diseases, inflammatory diseases, cancers, aging disorders, menopause, and osteoporosis.

Keywords: Medicinal yam, proteins, peptides, anti-oxidation, anti-microbial, anti-cancer, immunomodulation, menopause.

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Article Details

VOLUME: 20
ISSUE: 3
Year: 2019
Page: [277 - 284]
Pages: 8
DOI: 10.2174/1389203719666180622094356
Price: $58

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