Background: Cancer is considered one of the most predominant causes of morbidity and
mortality all over the world and colorectal cancer is the most common fatal cancers, triggering the
second cancer related death. Despite progress in understanding carcinogenesis and development in
chemotherapeutics, there is an essential need to search for improved treatment. More than the half a
century, cytotoxic and cytostatic agents have been examined as a potential treatment of cancer,
among these agents; remarkable progresses have been reported by the use of the snake venom.
Snake venoms are secreting materials of lethal snakes are store in venomous glands. Venoms are
composite combinations of various protein, peptides, enzymes, toxins and non proteinaceous secretions.
Conclusion: Snake venom possesses immense valuable mixtures of proteins and enzymes. Venoms
have potential to combat with the cancerous cells and produce positive effect. Besides the toxicological
effects of venoms, several proteins of snake venom e.g. disintegrins, phospholipases A2,
metalloproteinases, and L-amino acid oxidases and peptides e.g. bradykinin potentiators, natriuretic,
and analgesic peptides have shown potential as pharmaceutical agents, including areas of
diagnosis and cancer treatment. In this review we have discussed recent remarkable research that
has involved the dynamic snake venoms compounds, having anticancer bustle especially in case of