Recent Advances in the Synthesis of Heterocycles from Oximes (2014-2017)

Author(s): Edgars Abele* , Ramona Abele .

Journal Name: Current Organic Chemistry

Volume 22 , Issue 15 , 2018

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Graphical Abstract:


This review illustrates that oximes and their derivatives are valuable materials for the preparation of different classes of heterocyclic compounds. The main group of reactions included transition metal catalysed or transition metal-free cyclisation of unsaturated oximes. Using these starting materials pyrroles, isoxazoles, pyridines and isoquinolines were prepared. Some heterocyclic systems (for example, seven-membered rings) were obtained by the classical Beckmann rearrangement using novel reagents and conditions. Literature data published between January of 2014 and June of 2017 are included in this review.

Keywords: Oximes, heterocycles, three-membered heterocycles, pyrroles, oxadiazoles, pyridines, isoquinolines, seven-membered heterocycles.

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Article Details

Year: 2018
Page: [1486 - 1504]
Pages: 19
DOI: 10.2174/1385272822666180607095707
Price: $58

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