Role of BMAC in Avascular Necrosis
Pp. 75-79 (5)
Tomek Kowalski, Mohamed A. Imam, Kuen Chin and Martyn Snow
Avascular necrosis (AVN) is characterized by cell death of trabecular bone
leading to bone collapse and subsequent joint destruction. Recently, application of bone
marrow derived MSCs has been proposed as adjunctive treatment to core
decompression for osteonecrosis of femoral head. There have been several studies,
which report that BMAC application results in the improvement of outcomes;
nevertheless, it is dependent on the stage of osteonecrosis. Superior outcomes are
reported, similar to bone preserving procedures in the pre collapse stages. Additionally,
the technique has not been associated with any significant complications. The current
results are encouraging, however, more studies are required.
Avascular necrosis, Bone Marrow, Bone Marrow Aspirate
Concentrate (BMAC), Osteonecrosis, Stem Cells.
The Royal Orthopaedic Hospital, Northfield, Birmingham, UK.