Ethics in the Clinical Use and Research of Stem Cells and BMAC
Pp. 22-35 (14)
Ahmed Negida, Ahmed Elgebaly, Daniel Jackson and Mohamed A. Imam
Stem cell research is rapidly progressing especially in the field of
orthopaedic surgery. The processes of stem cell extraction, expansion, injection,
evaluation in preclinical studies and translation into human trials are challenging. Due
to the novelty and complexity of stem cell techniques, several methodological and
ethical issues need to be explored. Assessment of risk versus benefit proportionality,
selecting appropriate participants and determining a reliable therapeutic end point are
major challenges for stem cell trials in humans.
In this chapter, we are discussing ethical and methodological challenges in the clinical
use and research of stem cells and Bone Marrow Aspirate Cells.
Bone Marrow, Bone Marrow Aspirate Concentrate (BMAC), Ethics
in research, Stem Cells.
Faculty of Medicine, Zagazig University, Zagazig, El-Sharkia, 44519 Egypt.