Bone Marrow Aspirate Concentrate and Expanded Stem Cell Applications in Orthopaedics

Bone Marrow Aspirate Concentrate and Expanded Stem Cell Applications in Orthopaedics

This reference presents insights into the development of bone marrow aspirate stem cell (BMAC) technology and the potential role of stem cell expansion in the regeneration of damaged and deficient ...
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Introduction

Pp. 1-4 (4)

Mohamed A. Imam, Yasser Elsherbini and Martyn Snow

Abstract

Mesenchymal Stem Cells (MSCs) have multipotent plasticity. They demonstrate the ability to differentiate into various cell types. These include bone, tendon, cartilage, muscles and nerve [1-6]. Subsequently, they can have a role in the coming era of medicine as they have the potential to contribute to the regeneration and reconstruction of different tissues, especially in musculoskeletal medicine. As yet, Bone marrow is regarded as the most attractive source of MSCs [7, 8] and for the last few years, numerous interventionists have employed unprocessed Bone Marrow Aspirate (BMA), to incite healing.

Keywords:

Bone Marrow Aspirate Concentrate (BMAC), Expanded stem cells, MSCs.

Affiliation:

Department of Arthroscopy, The Royal Orthopaedic Hospital, Birmingham, UK.