Background: Breast cancer is the most widely occurring non-cutaneous cancer in women.
Treatment options available for breast cancer are limited and there are a number of toxicity concerns
associated with them. Therefore, nanocarrier based approaches have been explored for breast cancer
treatment. Nanocarriers implemented for breast cancer treatment are nanoliposomes, polymeric nanoparticles,
solid lipid nanoparticles, nanostructured lipid carriers, gold nanoparticles, dendrimers, and
Objective: Objective of this review was to explore the therapeutic efficacy of various nanocarrier systems
against breast cancer.
Method: Existing literature regarding nanocarrier systems for breast cancer therapy was reviewed using
Pubmed and Google Scholar.
Results: Nanocarriers may show prolonged circulation time of chemotherapeutic agent with efficient
breast tumor targeting. Both active and passive targeting methodologies can be explored to target
breast cancer cells using different nanocarriers. Targeted nanocarriers have the capability to reduce
side effects caused by various conventional formulations used to treat breast cancer.
Conclusion: Various nanocarriers listed above have shown their therapeutic potential in preclinical
studies to treat breast cancer. Satisfactory clinical evaluation and scale up techniques can promote
their entry into the pharmaceutical market in greater extent.