Background: There has been a phenomenal rise in the nanomaterial-based
cosmetic formulations in the market, raising serious concerns over the possible biological
impact on humans, animals and the environment as a whole. However, scarce reports
can be found on the safety assessment of nanomaterials incorporated in cosmetic formulations
including sunscreens. Hence, uncertainties loom for their safe use in cosmetics
including those applied dermatologically. Unfortunately, not much research has been
devoted to assess the safety profile of nanomaterials in cosmetics and the possible health
hazards. As a large number of nanotechnological sunscreen products containing diverse
sun filters against UV exposure are penetrating the market, the importance of adequate
assessment of nanomaterial exposure, its toxicokinetics including biodistribution, and
other health risks is now widely recognized.
Objective: The write up presents an overview of the nanomaterials used in sunscreen
products and discusses the various laws and regulations in force in various countries.
The review focuses on the current safety and regulation of nanomaterials in sunscreens.
Conclusion: While many countries have their own set of regulatory guidelines, it is high
time to have a globally acceptable guideline framework to protect both the consumers
and manufacturers for safe use, manufacture and sale of nanotechnology-based cosmetics.
Harmonization across the globe is desirable.