Polymorphism is a behavior of a substance to crystallize into more than one district crystal structures.
Preferential formation of a polymorph depends strongly on the kinetics of the relevant mechanisms. Solutionmediated
polymorphic transformation is an important mechanism in crystallization of organic compounds from
solution. Knowing its kinetics allows us to understand the process and control the polymorphic formation. In this
review, concepts, kinetics, and process modeling of crystallization and solution-mediated polymorphic transformation
are examined and summarized.
Keywords: Polymorphism, organic compound, crystallization from solution, kinetics, solution-mediated polymorphic transformation, process
Rights & PermissionsPrintExport