A Facile Procedure for Synthesis of Several 1, 4, 5-Trisubstituted-1Himidazole- 2(3H)-ones and -thiones via a One-pot Three-portion Reaction in Solvent and Microwave Irradiation

Author(s): Mohammad Shaker*.

Journal Name: Letters in Organic Chemistry

Volume 16 , Issue 2 , 2019

Graphical Abstract:


An ordinary procedure for the synthesis of several 1, 4, 5-trisubstituted-1H-imidazole- 2(3H)-ones and -thiones by a one-pot three-component reaction of glacial acetic acid under solvent, microwave irradiation condition is proposed. The products were formed through cyclization of benzoin with isothiocyanates or isocyanates and ammonium acetate. All incorporated combinations were determined for their spectral and microanalytical information. These compounds were subsequently studied for their fluorescence properties.

Keywords: Trisubstituted- 1H- imidazole- 2(3H)- ones and -thiones, multicomponent reactions, microwave irradiation, fluorescence, emission and absorption spectra, acetic acid.

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Article Details

Year: 2019
Page: [104 - 109]
Pages: 6
DOI: 10.2174/1570178615666180522101532
Price: $58

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PDF: 6