Tuber Lectins with Potentially Exploitable Bioactivities

Title:Tuber Lectins with Potentially Exploitable Bioactivities

Volume: 25 Issue: 42

Author(s): Randy Chi Fai Cheung, Jack Ho Wong*, Tzi Bun Ng*, Ryno Naude*, Krzysztof Rolka*, Ryan Tse, Tak Fu Tse*, Helen Chan*Stephen Cho Wing Sze*

Affiliation:

• School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong,China

• School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong,China

• Department of Biochemistry and Microbiology, Nelson Mandela Metropolitan University, Port Elizabeth,South Africa

• Department of Bioorganic Chemistry, University of Gdansk, Sobieskiego 18, 80-952 Gdansk,Poland

• Vita Green Pharmaceutical [Hong Kong] Ltd, Hong Kong Institute of Medical Research, and Genning Partners Company Limited, Hong Kong,China

• Vita Green Pharmaceutical [Hong Kong] Ltd, Hong Kong Institute of Medical Research, and Genning Partners Company Limited, Hong Kong,China

• Department of Biology, Faculty of Science, Hong Kong Baptist University, Hong Kong,China

Keywords: Antimicrobial, antioxidative, antitumor, hypoglycemic, immunomodulatory, insecticidal, mitogenic, nematicidal.

Abstract: Lectins are a group of proteins or glycoproteins with various potentially exploitable bioactivities and have been capturing more interest recently. They have been isolated and reported from various tissues of a diversity of plant species. Tubers are modified and enlarged plant structures derived from stems or roots that are used for nutrient storage and asexual reproduction. A number of plants such as yam, taro and potato are grown for their edible tubers, and lectins are found to be one of the major storage proteins. These lectins exhibit potent bioactivities encompassing mitogenic, antitumor, antimicrobial, immunomodulatory, antioxidative, hypoglycemic, insecticidal and nematicidal activities. They are potential resources for development into functional or healthy foods and targets for food protein researchers.

Cite this article as:

Cheung Chi Fai Randy , Wong Ho Jack *, Ng Bun Tzi *, Naude Ryno *, Rolka Krzysztof *, Tse Ryan , Tse Fu Tak *, Chan Helen *, Sze Cho Wing Stephen *, Tuber Lectins with Potentially Exploitable Bioactivities, Current Medicinal Chemistry 2018; 25 (42) . https://dx.doi.org/10.2174/0929867325666180517095308