Soft Biomaterial-based Nanocrystal in Pharmaceutical

Author(s): Nandi Chen, Taojunfeng Su, Zhe Cheng*, Feifei An*.

Journal Name: Current Pharmaceutical Design

Volume 24 , Issue 21 , 2018


Abstract:

Background and Objective: Bio-soft material, a class of derivatives of the natural or synthetic material, is getting more and more prevalent in biomedical researches and applications due to the advantages such as in-vivo biodegradation, good water solubility and designable targeting ability. With the presence of bio-soft materials, the drug nanocrystal can be easily generated and aggregated in a feasible process. Given the promising application of the bio-soft material in biological and chemical research, it is valuable to discuss the crucial step in designing bio-soft materials and analyze the emerging properties of bio-soft materials.

Methods: A comprehensive literature survey in the field of bio-soft material development and analysis has been conducted. The collected data and figures were meticulously analyzed and interpreted.

Results: In this review, the details of bio-soft materials based nanocrystal were demonstrated in three sections with respect to different materials. In each section, the pros and cons for each bio-soft material and its derivatives were elaborately listed and discussed.

Conclusion: The review enables an insightful discussion about the properties and the applications of existing biosoft material. It may contribute to the further researches about bio-soft material development and analysis.

Keywords: Nanocrystal, nucleic acid, peptide, protein, albumin, ferritin.

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Article Details

VOLUME: 24
ISSUE: 21
Year: 2018
Page: [2349 - 2361]
Pages: 13
DOI: 10.2174/1381612824666180515154848
Price: $58

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