Background: In recent years, nanotechnology-based biomedical platforms aid
characteristic dimensions in the field of biomedicine as compared to the conventional
strategies. This nanotechnological intervention carries widespread biomedical avenues in
the diagnosis and treatment of an array of dreadful diseases.
Objective: Silver nanoparticles (AgNPs) have the inherent property of immense biological
potential such as antimicrobial and anticancer activity. AgNPs also show tremendous
optical and electrical properties suggesting its candidature as promising bio-sensing agent
thereby promoting environmental and biological management. The use of AgNPs as contrast
agents could be exploited for enhanced bio-imaging of cellular and sub-cellular organelles
giving insight into the mechanism of action of the administered drugs. More importantly,
functionalized AgNPs have been driven a new wave of innovation in developing
targeted drug delivery and theranostics. In this article, we summarize the current
status and progress of functionalized AgNPs-based nanoplatform for biomedical applications
with an emphasis on sensing, molecular imaging, and theranostics.
Main Text: The present review focuses on the importance of functionalized AgNPs towards
enhanced biosensing, bio-imaging and theranostics applications as compared to the
conventional modalities. It also clarifies the importance of functionalization to increase
the efficacy of bio-sensing, bio-imaging and theranostic modalities.
Future Perspectives: The present review not only emphasizes the biomedical importance
of functionalized AgNPs but also scrutinizes its widespread avenues in the near future for
the transformation into clinical translation.