DNA-functionalized nanoparticle (DfNP) technology, the integration of DNA with
nanotechnology, has emerged over recent decades as a promising biofunctionalization tool in
the light of biotechnological approaches. The development of DfNPs has exhibited significant
potential for several biological and biomedical applications. In this review, we focus on the
mechanism of a series of DNA-NP nanocomposites and highlight the superstructures of
DNA-based NPs. We also summarize the applications of these nanocomposites in cell imaging,
cancer therapy and bioanalytical detection.
Keywords: DNA, nanoparticle, cancer therapy and imaging, bioanalysis, biofunctionalization, biomedical applications.
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