Research Progress of Progesterone Preparations: A Mini Review

Author(s): Mingzhu Ye, Weisan Pan*, Xinggang Yang*, Xiaoyu Zhang.

Journal Name: Current Drug Metabolism

Volume 19 , Issue 10 , 2018

Graphical Abstract:


Background: Progesterone is a sex steroid hormone. Since it has been discovered, it is widely used in the prevention of spontaneous preterm birth, hormone replacement therapy and other gynecological conditions.

Methods: We will review the progesterone preparations based on a comprehensive study of papers and patents from the traditional preparations up through the very recent literatures.

Results: This review mainly concentrates on oral, vaginal and micro delivery systems, involving different ways to prepare progesterone preparations.

Conclusion: Although progesterone has first-pass effects, with these methods, the bioavailability and compliance can be greatly increased.

Keywords: Delivery system, injection, microspheres, oral, progesterone preparations, vaginal.

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Article Details

Year: 2018
Page: [871 - 875]
Pages: 5
DOI: 10.2174/1389200219666180427165438
Price: $58

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