This review summarizes the literature data regarding plant lectins as novel drug sources in the
prevention or treatment of cancer. Moreover, such compounds have been described as natural toxins that possess
different biological activities (cytotoxic, antitumor, antimutagenic and anticarcinogenic properties). This activity
depends greatly on their structure and affinity. Most of the mushroom heterosides are known as β-glucans with
β-(1→3)-glycosidic bonds. It is thought that their conformation, bonds, molecular size can modulate the
immune response by triggering different receptors. The mechanism on normal and tumor cells of various plant
and mushroom polysaccharides and lectins is briefly presented in this paper.
Keywords: Cancer, plant lectins, mushroom, mechanism, apoptosis, receptors.
Rights & PermissionsPrintExport