Objective: In order to test real direct applicability for analytical purposes, a small and simple
direct methanol (or ethanol) catalytic, enzymatic or non-enzymatic fuel cell (DMFC) was used for
the analysis of ethanol-based pharmaceutical tinctures; a detailed experimental study was conducted
on five different pharmaceutical tinctures available at drugstores.
Results: The results obtained using both enzymatic and non-enzymatic devices were compared with
those obtained by analyzing the same pharmaceutical samples with a conventional catalase biosensor.
Finally, the results were compared with the nominal values provided by manufacturing firms.
Conclusion: The correlations between the different experimental and nominal values considered were
good in general or satisfactory and the applied statistical tests (f-test and t-test) were also very comforting.
At the end of the study, the use of enzymatic DMFC proved to be better than non- enzymatic
DMFC devices, because it requires shorter analysis times.