Title:Electrospun Fibers for Cartilage Tissue Regeneration
VOLUME: 13 ISSUE: 7
Author(s):Guo Li, Sirong Shi, Shiyu Lin, Tengfei Zhou, Xiaoru Shao, Qiao Huang, Bofeng Zhu and Xiaoxiao Cai*
Affiliation:State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, Department of Forensic Genetics, School of Forensic Medicine, Southern Medical University, Guangzhou 510515, State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu
Keywords:Electrospun, tissue engineering, electrospinning materials, stem cell, biomaterials, cartilage.
Abstract:Background: Cartilage injury has always been puzzled for clinicians. The treatments used
clinically for cartilage injury usually bring about fibrocartilage. The emergence of tissue engineering
lights up the hope of cartilage repair.
Objective: This review will sum up the existing learnings about electrospun fibers, revolving about the
electrospinning materials, micromorphology, improvements and electrospun technologies newly developed
in cartilage repair and regeneration.
Results: Electrospun fibers as scaffolds for cartilage regeneration have been one of researching hotspots
for years. The studies about new electrospun materials and new electrospinning technologies
greatly promoted the development of this field.
Conclusion: Electrospun fibers have showed great potential in cartilage regeneration. But there is still
a long way to go before clinical application. The material embellishment and structure imitation should
be highlighted in future.