Probiotics and Prebiotics as Functional Foods: State of the Art

Author(s): Amin Mousavi Khaneghah*, Yadolah Fakhri.

Journal Name: Current Nutrition & Food Science

Volume 15 , Issue 1 , 2019

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Abstract:

Foods, besides their nutritional value, are used to be as a tool in maintaining of physical and mental well-being and prevent disease. Based on the definition of Functional foods as foods, which may offer health benefits beyond basic nutrition, functional foods, are categorized as foods, not medicine. Among the last decades, the growing market for functional foods, representing both opportunities and challenges to food producers as well academic sections to cover such demand and furthermore conquer the acceptance of consumer. In this article, an overview regarding the probiotics as well as prebiotics as outstanding components of functional foods, compatibility and their use in food products have been reviewed.

Keywords: Consumer, functional foods, gut flora, prebiotics, probiotics, technology.

[1]
Jafari M, Mortazavian AM, Hosseini H, Safaei F, Khaneghah AM, Sant’Ana AS. Probiotic Bacillus: Fate during sausage processing and storage and influence of different culturing conditions on recovery of their spores. Food Res Int 2017; 95: 46-51.
[2]
Hashemi SMB, Khaneghah AM, Barba FJ, Nemati Z, Shokofti SS, Alizadeh F. Fermented sweet lemon juice (Citrus limetta) using Lactobacillus plantarum LS5: Chemical composition, antioxidant and antibacterial activities. J Funct Foods 2017; 38: 409-14.
[3]
Hasani S, Khodadadi I, Heshmati A. Viability of Lactobacillus acidophilus in rice bran‐enriched stirred yoghurt and the physicochemical and sensory characteristics of product during refrigerated storage. Int J Food Sci Technol 2016; 51(11): 2485-92.
[4]
Hashemi SMB, Khaneghah AM, Fidelis M, Granato D. Effects of pulsed thermosonication treatment on fungal growth and bioactive compounds of Berberis vulgaris juice. Int J Food Sci Technol 2018; 1589-96.
[5]
Hashemi SMB, Mousavi Khaneghah A, Kontominas MG, et al. Fermentation of sarshir (kaymak) by lactic acid bacteria: Antibacterial activity, antioxidant properties, lipid and protein oxidation and fatty acid profile. J Sci Food Agric 2017; 97(13): 4595-603.
[6]
Viljanen M, Savilahti E, Haahtela T, et al. Probiotics in the treatment of atopic eczema/dermatitis syndrome in infants: A double‐blind placebo‐controlled trial. Allergy 2005; 60(4): 494-500.
[7]
Randazzo C, Pitino I, Ribbera A, Caggia C. Pecorino crotonese cheese: Study of bacterial population and flavour compounds. Food Microbiol 2010; 27(3): 363-74.
[8]
Pitino I, Randazzo CL, Mandalari G, et al. Survival of Lactobacillus rhamnosus strains in the upper gastrointestinal tract. Food Microbiol 2010; 27(8): 1121-7.
[9]
Del Piano M, Morelli L, Strozzi G, et al. Probiotics: From research to consumer. Dig Liver Dis 2006; 38: S248-55.
[10]
Vardakou M, Mercuri A, Barker SA, Craig DQ, Faulks RM, Wickham MS. Achieving antral grinding forces in biorelevant in vitro models: Comparing the USP dissolution apparatus II and the dynamic gastric model with human in vivo data. AAPS PharmSciTech 2011; 12(2): 620-6.
[11]
Forestier C, De Champs C, Vatoux C, Joly B. Probiotic activities of Lactobacillus casei rhamnosus: In vitro adherence to intestinal cells and antimicrobial properties. Res Microbiol 2001; 2(152): 167-73.
[12]
da Cruz AG, Buriti FCA, de Souza CHB, Faria JAF, Saad SMI. Probiotic cheese: Health benefits, technological and stability aspects. Trends Food Sci Technol 2009; 20(8): 344-54.
[13]
Phillips M, Kailasapathy K, Tran L. Viability of commercial probiotic cultures (L. acidophilus, Bifidobacterium sp., L. casei, L. paracasei and L. rhamnosus) in cheddar cheese. Int J Food Microbiol 2006; 108(2): 276-80.
[14]
Gupta S, Abu-Ghannam N. Probiotic fermentation of plant based products: Possibilities and opportunities. Crit Rev Food Sci Nutr 2012; 52(2): 183-99.
[15]
Hayes M, Coakley M, O’sullivan L, Stanton C. Cheese as a delivery vehicle for probiotics and biogenic substances. Aust J Dairy Technol 2006; 61(2): 132.
[16]
Kuisma J, Mentula S, Jarvinen H, Kahri A, Saxelin M, Farkkila M. Effect of Lactobacillus rhamnosus GG on ileal pouch inflammation and microbial flora. Aliment Pharmacol Ther 2003; 17(4): 509-15.
[17]
Mainville I, Arcand Y, Farnworth E. A dynamic model that simulates the human upper gastrointestinal tract for the study of probiotics. Int J Food Microbiol 2005; 99(3): 287-96.
[18]
Burns P, Patrignani F, Serrazanetti D, et al. Probiotic Crescenza cheese containing Lactobacillus casei and Lactobacillus acidophilus manufactured with high-pressure homogenized milk. J Dairy Sci 2008; 91(2): 500-12.
[19]
Brinques GB, Ayub MAZ. Effect of microencapsulation on survival of Lactobacillus plantarum in simulated gastrointestinal conditions, refrigeration, and yogurt. J Food Eng 2011; 103(2): 123-8.
[20]
Huang Y, Adams MC. In vitro assessment of the upper gastrointestinal tolerance of potential probiotic dairy propionibacteria. Int J Food Microbiol 2004; 91(3): 253-60.
[21]
Curto AL, Pitino I, Mandalari G, Dainty JR, Faulks RM, Wickham MSJ. Survival of probiotic lactobacilli in the upper gastrointestinal tract using an in vitro gastric model of digestion. Food Microbiol 2011; 28(7): 1359-66.
[22]
Hua W, Yang X, Yonghua X, Feng X, Gengpin L. Synergistic antidigestion effect of Lactobacillus rhamnosus and bovine colostrums in simulated gastrointestinal tract (in vitro). Appl Microbiol Biotechnol 2007; 75(3): 619-26.
[23]
Corbo M, Albenzio M, De Angelis M, Sevi A, Gobbetti M. Microbiological and biochemical properties of Canestrato Pugliese hard cheese supplemented with bifidobacteria. J Dairy Sci 2001; 84(3): 551-61.
[24]
Cruz AG, Antunes AE, Sousa ALO, Faria JA, Saad SM. Ice-cream as a probiotic food carrier. Food Res Int 2009; 42(9): 1233-9.
[25]
Heller KJ. Probiotic bacteria in fermented foods: Product characteristics and starter organisms. Am J Clin Nutr 2001; 73(2): 374s-9s.
[26]
Capela P, Hay T, Shah N. Effect of cryoprotectants, prebiotics and microencapsulation on survival of probiotic organisms in yoghurt and freeze-dried yoghurt. Food Res Int 2006; 39(2): 203-11.
[27]
Gupta S, Cox S, Abu-Ghannam N. Process optimization for the development of a functional beverage based on lactic acid fermentation of oats. Biochem Eng J 2010; 52(2-3): 199-204.
[28]
Heenan C, Adams M, Hosken R, Fleet G. Survival and sensory acceptability of probiotic microorganisms in a nonfermented frozen vegetarian dessert. LWT-Food Sci Technol 2004; 37(4): 461-6.
[29]
Ding W, Shah NP. Survival of free and microencapsulated probiotic bacteria in orange and apple juices. Int Food Res J 2008; 15(2): 219-32.
[30]
Biedrzycka E, Bielecka M. Prebiotic effectiveness of fructans of different degrees of polymerization. Trends Food Sci Technol 2004; 15(3): 170-5.
[31]
Cunningham-Rundles S, Ahrné S, Bengmark S, et al. Probiotics and immune response. Am J Gastroenterol 2000; 95(1): S22-5.
[32]
Gouin S. Microencapsulation: Industrial appraisal of existing technologies and trends. Trends Food Sci Technol 2004; 15(7): 330-47.
[33]
Chou C-C, Hou J-W. Growth of bifidobacteria in soymilk and their survival in the fermented soymilk drink during storage. Int J Food Microbiol 2000; 56(2-3): 113-21.
[34]
Campbell JM, Fahey GC, Wolf BW. Selected indigestible oligosaccharides affect large bowel mass, cecal and fecal short-chain fatty acids, pH and microflora in rats. J Nutr 1997; 127(1): 130-6.
[35]
Charalampopoulos D, Wang R, Pandiella S, Webb C. Application of cereals and cereal components in functional foods: A review. Int J Food Microbiol 2002; 79(1-2): 131-41.
[36]
Godward G, Kailasapathy K. Viability and survival of free and encapsulated probiotic bacteria in Cheddar cheese. Milchwissenschaft 2003; 58(11-12): 624-7.
[37]
Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001; 73(2): 415s-20s.
[38]
Annan N, Borza A, Hansen LT. Encapsulation in alginate-coated gelatin microspheres improves survival of the probiotic Bifidobacterium adolescentis 15703T during exposure to simulated gastro-intestinal conditions. Food Res Int 2008; 41(2): 184-93.
[39]
Burgain J, Gaiani C, Linder M, Scher J. Encapsulation of probiotic living cells: From laboratory scale to industrial applications. J Food Eng 2011; 104(4): 467-83.
[40]
Gbassi GK, Vandamme T. Probiotic encapsulation technology: From microencapsulation to release into the gut. Pharmaceutics 2012; 4(1): 149-63.
[41]
Bielecka M, Biedrzycka E, Majkowska A. Selection of probiotics and prebiotics for synbiotics and confirmation of their in vivo effectiveness. Food Res Int 2002; 35(2): 125-31.
[42]
Champagne C, Fustier P, Saarela M. Microencapsulation for delivery of probiotics and other ingredients in functional dairy products. In: Functional dairy products. Vol. 2, 2007; Elsevier: Amsterdam, Netherlands, pp: 404-26.
[43]
Champagne CP, Fustier P. Microencapsulation for the improved delivery of bioactive compounds into foods. Curr Opin Biotechnol 2007; 18(2): 184-90.
[44]
de Vos P, Faas MM, Spasojevic M, Sikkema J. Encapsulation for preservation of functionality and targeted delivery of bioactive food components. Int Dairy J 2010; 20(4): 292-302.
[45]
Giovannini M, Agostoni C, Riva E, et al. A randomized prospective double blind controlled trial on effects of long-term consumption of fermented milk containing Lactobacillus casei in pre-school children with allergic asthma and/or rhinitis. Pediatr Res 2007; 62(2): 215-20.
[46]
Joint F. WHO working group report on drafting guidelines for the evaluation of probiotics in food. London, Ontario, Canada 2002; p. 30.
[47]
Fazeli M, Amirmozafari N, Jamalifar H. Antagonistic action of watermelon juice probioticated using different strains of Lactobacilli against Salmonella typhimurium. Iran J Public Health 2007; 36(4): 70-3.
[48]
Pehkonen K, Roos Y, Miao S, Ross R, Stanton C. State transitions and physicochemical aspects of cryoprotection and stabilization in freeze‐drying of Lactobacillus rhamnosus GG (LGG). J Appl Microbiol 2008; 104(6): 1732-43.
[49]
De Vuyst L, Falony G, Leroy F. Probiotics in fermented sausages. Meat Sci 2008; 80(1): 75-8.
[50]
Gueimonde M, Delgado S, Mayo B, Ruas-Madiedo P, Margolles A, de los Reyes-Gavilán CG. Viability and diversity of probiotic Lactobacillus and Bifidobacterium populations included in commercial fermented milks. Food Res Int 2004; 37(9): 839-50.
[51]
Borgogna M, Bellich B, Zorzin L, Lapasin R, Cesàro A. Food microencapsulation of bioactive compounds: Rheological and thermal characterisation of non-conventional gelling system. Food Chem 2010; 122(2): 416-23.
[52]
Favaro-Trindade C, Grosso C. Microencapsulation of L. acidophilus (La-05) and B. lactis (Bb-12) and evaluation of their survival at the pH values of the stomach and in bile. J Microencapsul 2002; 19(4): 485-94.
[53]
Salem MM, Fathi FA, Awad R. Production of probiotic ice cream. Pol J Food Nutr Sci 2005; 14(3): 267.
[54]
Rodgers S. Novel applications of live bacteria in food services: Probiotics and protective cultures. Trends Food Sci Technol 2008; 19(4): 188-97.
[55]
Vasudha S, Mishra H. Non dairy probiotic beverages. Int Food Res J 2013; 20(1): 7-15.
[56]
Kun S, Rezessy-Szabó JM, Nguyen QD, Hoschke Á. Changes of microbial population and some components in carrot juice during fermentation with selected Bifidobacterium strains. Process Biochem 2008; 43(8): 816-21.
[57]
Granato D, Branco GF, Nazzaro F, Cruz AG, Faria JA. Functional foods and nondairy probiotic food development: Trends, concepts, and products. Compr Rev Food Sci Food Saf 2010; 9(3): 292-302.
[58]
Pineiro M, Stanton C. Probiotic bacteria: Legislative framework-requirements to evidence basis. J Nutr 2007; 137(3): 850S-3S.
[59]
Adhikari K, Mustapha A, Grün I. Survival and metabolic activity of microencapsulated Bifidobacterium longum in stirred yogurt. J Food Sci 2003; 68(1): 275-80.
[60]
Vasile A, Paraschiv D, Dima S, Bahrim G. Growth and cell viability improve of the probiotic strain Lactobacillus casei ssp. paracasei in the presence of oat bran and buckwheat flour. Innov Rom Food Biotechnol 2011; 9: 52.
[61]
Pereira ALF, Maciel TC, Rodrigues S. Probiotic beverage from cashew apple juice fermented with Lactobacillus casei. Food Res Int 2011; 44(5): 1276-83.
[62]
Chen MJ, Chen KN. Applications of probiotic encapsulation in dairy products.Encapsulation and controlled release technologies in food systems. New Jersey, United States: Wiley 2007; pp. 83-112.
[63]
Andersson H, Asp N-G, Bruce Å, Roos S, Wadström T, Wold AE. Health effects of probiotics and prebiotics. A literature review on human studies. Food Nutr Res 2001; 45: 58-75.
[64]
Hartemink R, Rombouts F. Gas formation from oligosaccharides by the intestinal microflora.
[65]
de Vrese M, Winkler P, Rautenberg P, et al. Effect of Lactobacillus gasseri PA 16/8, Bifidobacterium longum SP 07/3, B. bifidum MF 20/5 on common cold episodes: A double blind, randomized, controlled trial. Clin Nutr 2005; 24(4): 481-91.
[66]
Bezkorovainy A. Probiotics: Determinants of survival and growth in the gut. Am J Clin Nutr 2001; 73(2): 399s-405s.
[67]
Anal AK, Singh H. Recent advances in microencapsulation of probiotics for industrial applications and targeted delivery. Trends Food Sci Technol 2007; 18(5): 240-51.
[68]
Ding W, Shah N. Acid, bile, and heat tolerance of free and microencapsulated probiotic bacteria. J Food Sci 2007; 72(9): M446-50.
[69]
Chávarri M, Marañón I, Ares R, Ibáñez FC, Marzo F, del Carmen Villarán M. Microencapsulation of a probiotic and prebiotic in alginate-chitosan capsules improves survival in simulated gastro-intestinal conditions. Int J Food Microbiol 2010; 142(1): 185-9.
[70]
Diop L, Guillou S, Durand H. Probiotic food supplement reduces stress-induced gastrointestinal symptoms in volunteers: A double-blind, placebo-controlled, randomized trial. Nutr Res 2008; 28(1): 1-5.
[71]
Anjani K, Iyer C, Kailasapathy K. Survival of co-encapsulated complementary probiotics and prebiotics in yoghurt. Milchwissenschaft 2004; 59(7-8): 396-9.
[72]
Shi L-E, Li Z-H, Zhang Z-L, et al. Encapsulation of Lactobacillus bulgaricus in carrageenan-locust bean gum coated milk microspheres with double layer structure. LWT-Food Sci Technol 2013; 54(1): 147-51.
[73]
Roy D, Delcenserie V. The protective role of probiotics in disturbed enteric microbiota.Probiotic Bacteria and Enteric Infections. Berlin, Germany: Springer 2011; pp. 221-61.
[74]
Thirabunyanon M, Thongwittaya N. Protection activity of a novel probiotic strain of Bacillus subtilis against Salmonella Enteritidis infection. Res Vet Sci 2012; 93(1): 74-81.
[75]
Mansour NM, Heine H, Abdou SM, Shenana ME, Zakaria MK, El‐Diwany A. Isolation of Enterococcus faecium NM113, Enterococcus faecium NM213 and Lactobacillus casei NM512 as novel probiotics with immunomodulatory properties. Microbiol Immunol 2014; 58(10): 559-69.
[76]
Górska S, Hermanova P, Ciekot J, et al. Chemical characterization and immunomodulatory properties of polysaccharides isolated from probiotic Lactobacillus casei LOCK 0919. Glycobiology 2016; 26(9): 1014-24.
[77]
Chiu Y-H, Tsai J-J, Lin S-L, Chotirosvakin C, Lin M-Y. Characterisation of bifidobacteria with immunomodulatory properties isolated from human breast milk. J Funct Foods 2014; 7: 700-8.
[78]
Feng J, Wang L, Zhou L, Yang X, Zhao X. Using in vitro immunomodulatory properties of lactic acid bacteria for selection of probiotics against Salmonella infection in broiler chicks. PLoS One 2016; 11(1): e0147630.
[79]
Zagato E, Mileti E, Massimiliano L, et al. Lactobacillus paracasei CBA L74 metabolic products and fermented milk for infant formula have anti-inflammatory activity on dendritic cells in vitro and protective effects against colitis and an enteric pathogen in vivo. PLoS One 2014; 9(2): e87615.
[80]
Rieu A, Aoudia N, Jego G, et al. The biofilm mode of life boosts the anti‐inflammatory properties of Lactobacillus. Cell Microbiol 2014; 16(12): 1836-53.
[81]
Kawahara M, Nemoto M, Nakata T, et al. Anti-inflammatory properties of fermented soy milk with Lactococcus lactis subsp. lactis S-SU2 in murine macrophage RAW264. 7 cells and DSS-induced IBD model mice. Int Immunopharmacol 2015; 26(2): 295-303.
[82]
Sah B, Vasiljevic T, McKechnie S, Donkor O. Effect of probiotics on antioxidant and antimutagenic activities of crude peptide extract from yogurt. Food Chem 2014; 156: 264-70.
[83]
Apás AL, González SN, Arena ME. Potential of goat probiotic to bind mutagens. Anaerobe 2014; 28: 8-12.
[84]
Lim S-M. Antimutagenicity activity of the putative probiotic strain Lactobacillus paracasei subsp. tolerans JG22 isolated from pepper leaves Jangajji. Food Sci Biotechnol 2014; 23(1): 141-50.
[85]
Amaretti A, Di Nunzio M, Pompei A, Raimondi S, Rossi M, Bordoni A. Antioxidant properties of potentially probiotic bacteria: In vitro and in vivo activities. Appl Microbiol Biotechnol 2013; 97(2): 809-17.
[86]
Shakibaie M, Mohammadi-Khorsand T, Adeli-Sardou M, et al. Probiotic and antioxidant properties of selenium-enriched Lactobacillus brevis LSe isolated from an Iranian traditional dairy product. J Trace Elem Med Biol 2017; 40: 1-9.
[87]
Lamari F, Mahdhi A, Chakroun I, et al. Interactions between candidate probiotics and the immune and antioxidative responses of European sea bass (Dicentrarchus labrax) larvae. J Fish Dis 2016; 39(12): 1421-32.


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Article Details

VOLUME: 15
ISSUE: 1
Year: 2019
Page: [20 - 30]
Pages: 11
DOI: 10.2174/1573401314666180416120241
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