Dementia has become a major health concern for the aging population of the United States. Studies
indicate that participation in moderate exercise, with training, has been shown to have a beneficial impact on
cognition. Thus, exercise and its effects on cognitive function has become an important area of research. This
review summarizes the current literature on the potential mechanisms of the benefits of exercise for cognitive
Keywords: Cognitive function, dementia, exercise, BDNF, PGC-1α, IL-6.
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