Background: A series of novel 2,6-dichloro-4-(trifluoromethyl)phenyl)-3-(difluoromethyl)-
1H-pyrazole-4-carboxamide derivatives were designed and synthesized.
Methods: All the title compounds were confirmed by 1H NMR and MS.
Results and Conclusion: The primarily nematicidal activity results indicated that some of them
exhibited moderate control efficacy against the tomato root-knot nematode disease caused by
Keywords: Difluoromethylpyrazole, alkyl chain, nematicidal activity, synthesis, docking, Meloidogyne incognita.
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