Synthesis of (2-iminomethyl)pyridine Moiety Supported on Hydroxyapatiteencapsulated-γ-Fe2O3 as an Inorganic-organic Hybrid Magnetic Nanocatalyst for the Synthesis of Thiazole Derivatives under Ultrasonic Irradiation

Author(s): Mohammad Ahmadiazar , Manouchehr Mamaghani* .

Journal Name: Current Organic Chemistry

Volume 22 , Issue 13 , 2018

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Abstract:

A novel pyridine base modified core-shell (γ-Fe2O3@Hap (Hap: Hydroxyapatite)) inorganic-organic hybrid magnetic nanocatalyst has been introduced. The catalyst was fully characterized by spectroscopic analyses (FT-IR, FESEM, EDX, XRD) and its efficiency evaluated as a basic catalyst in one-pot multicomponent reaction of aryl aldehydes, rhodanine and piperidine under ultrasonic irradiation to obtain thiazole derivatives. This green, fast and straightforward protocol produced the products in short reaction times (14-40 min) and high to excellent yields (75-95%).

Keywords: γ-Fe2O3@HAp, thiazole, rhodanine, thiazolone, ultrasonic irradiation, multicomponent reaction.

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Article Details

VOLUME: 22
ISSUE: 13
Year: 2018
Page: [1326 - 1334]
Pages: 9
DOI: 10.2174/1385272822666180322121544
Price: $58

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