Background: Cancer nanotechnology has become a prime field of investigations
for the scientists nowadays. There are several nanocarrier systems used for effective
cancer therapeutics and gold nanoparticles (GNPs/AuNPs) have become promising vehicles
for the delivery of anticancer drugs into their targets. Gold nanoparticles
(GNPs/AuNPs) have been explored for tumor targeting, tumor imaging, and photothermal
therapy of cancer due to their unique physicohemical and optical characteristics.
Methods: We searched about recent research progress made in the field of gold nanoparticulate
systems for effective elimination of cancer. Our main focus was on the use of
gold nanoparticles (spherical), gold nanorods, and gold nanostars for improved cancer
Results: Gold nanoparticles are suited well for cancer therapeutics due to their higher
biocompatibility and lesser toxicity. They can be utilized actively or passively both for
the targeting of tumor cells.
Conclusion: Recently, gold nanoparticulates have been investigated preclinically for the
treatment of cancer. Their clinical practice is still a challenge and it is necessary to carry
out clinical practice of gold nanoparticles to make them available in the market. Future
advancement in the field of gold nanoparticles will likely produce better results in cancer