The risk of bacterial colonization of abiotic surfaces of biomedical devices poses important challenges
for the pharmaceutical and biomaterials science fields. In this scenario, antibacterial coatings have been developed,
using a number of different molecules and materials. Among them, chitosan is a non-cytotoxic, biocompatible
biopolymer with an inherent antimicrobial activity that has been already used in a wide variety of
healthcare and industrial applications. Herein, chitosan-based antibacterial coatings are critically surveyed, with a
special emphasis on their production methods, pharmaceutical and biomedical applications, along with their pros
and cons, and finally highlighting the key challenges to be faced and future perspectives in this field.
Keywords: Chitosan, antibacterial coatings, biomedical devices, biofilm, contact-killing surfaces, biocompatibility, physisorption, grafting.
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