Background: Polyhydroxyalkanoates are bio-based, biodegradable naturally occurring polymers
produced by a wide range of organisms, from bacteria to higher mammals. The properties and biocompatibility
of PHA make it possible for a wide spectrum of applications. In this context, we analyze the potential applications
of PHA in biomedical science by exploring the global trend through the patent survey. The survey suggests
that PHA is an attractive candidate in such a way that their applications are widely distributed in the medical
industry, drug delivery system, dental material, tissue engineering, packaging material as well as other useful
Objective: In our present study, we explored patents associated with various biomedical applications of polyhydroxyalkanoates.
Method: Patent databases of European Patent Office, United States Patent and Trademark Office and World
Intellectual Property Organization were mined. We developed an intensive exploration approach to eliminate
overlapping patents and sort out significant patents.We demarcated the keywords and search criterions and established
search patterns for the database request. We retrieved documents within the recent 6 years, 2010 to
2016 and sort out the collected data stepwise to gather the most appropriate documents in patent families for
Results: By this approach, we retrieved 23,368 patent documents from all the three databases and the patent titles
were further analyzed for the relevance of polyhydroxyalkanoates in biomedical applications. This ensued
in the documentation of approximately 226 significant patents associated with biomedical applications of polyhydroxyalkanoates
and the information was classified into six major groups. Polyhydroxyalkanoates has been
patented in such a way that their applications are widely distributed in the medical industry, drug delivery system,
dental material, tissue engineering, packagingmaterial as well as other useful products.
Conclusion: There are many avenues through which PHA & PHB could be used. Our analysis shows patent
information can be used to identify various applications of PHA and its representatives in the biomedical field.
Upcoming studies can focus on the application of PHA in the different field to discover the related topics and
associate to this study.We believe that this approach of analysis and findings can initiate new researchers to undertake
similar kind of studies in their represented field to fill the gap between the patent articles and research