Thrombolytic Therapy in the Current ERA: Myocardial Infarction and Beyond

Author(s): Patrick Proctor, Massoud A. Leesar, Arka Chatterjee*.

Journal Name: Current Pharmaceutical Design

Volume 24 , Issue 4 , 2018

Abstract:

Thrombolytic therapy kick-started the era of modern cardiology but in the last few decades it has been largely supplanted by primary percutaneous coronary intervention (PCI) as the go-to treatment for acute myocardial infarction. However, these agents remain important for vast populations without access to primary PCI and acute ischemic stroke. More innovative uses have recently come up for the treatment of a variety of conditions. This article summarizes the history, evidence base and current use of thrombolytics in cardiovascular disease.

Keywords: Thrombolysis, acute myocardial infarction, catheter directed thrombolysis, pulmonary embolism, acute ischemic stroke, thrombolytic therapy.

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Article Details

VOLUME: 24
ISSUE: 4
Year: 2018
Page: [414 - 426]
Pages: 13
DOI: 10.2174/1381612824666171227211623
Price: $58

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