Catalytic asymmetric hydrosilylation based on the use of inexpensive and
handleable hydridic silanes is a very useful reaction in organic chemistry which has become
the subject of special interest because of the intrinsic peculiarity of economic efficiency
and environmental friendliness. Recently, a lot of structurally diverse organocatalysts
have been designed and applied to this chemistry. Enantiopure organocatalysts such
as formamide derivatives, picolinamide derivatives, S-chiral sulfinamide derivatives and
chiral frustrated Lewis pairs (FLPs) have been proved as privileged catalysts for the enantioselective
hydrosilylations. This manuscript provides an overview on the most relevant
advances in this field and presents an extensive summary of the catalysis performance of
the above mentioned catalysts.
Keywords: Asymmetric reduction, hydrosilylations, organocatalysts, hydridic silanes, asymmetric synthesis, Lewis Bases.
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