A novel synthesis of 3-(7-methylbenzo[d]oxazol-4-yl) butanoic acid as a possible precursor
of (+)-seco-pseudopteroxazole and (+)-pseudopteroxazole is presented. This synthesis was performed
from m-cresol where a Fries rearrangement, a nitration reaction and an olefination reaction were the
key reactions to achieve the synthesis of 3-(7-methylbenzo[d]oxazol-4-yl) butanoic acid.
Keywords: (+)-seco-pseudopteroxazole, (+)-pseudopteroxazole, antituberculotic, Mycobacterium tuberculosis, nitration reaction,
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