Background: Quinoxaline-based derivatives present a group of very important heterocyclic
pharmacophores which occupied the attention of a large number of scientists in the last few decades.
Compounds with quinoxaline fragment have significant antitumor and antiviral potential, proved by an
in vitro or/and in vivo study, and possess therapeutic potential.
Conclusion: In this review article, we present an overview of the developments in the area of synthesis
of compounds that contain quinoxaline scaffold with antitumor or antiviral activities.
Keywords: o-Phenylenediamine, Diketo acid, quinoxaline, antitumor activity, antiviral activity, benzodiazepene.
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