Synthesis of Quinoxaline-Based Compounds and Their Antitumor and Antiviral Potentials

Author(s): Jelena Petronijevic*, Nenad Jankovic, Zorica Bugarcic.

Journal Name: Mini-Reviews in Organic Chemistry

Volume 15 , Issue 3 , 2018

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Abstract:

Background: Quinoxaline-based derivatives present a group of very important heterocyclic pharmacophores which occupied the attention of a large number of scientists in the last few decades. Compounds with quinoxaline fragment have significant antitumor and antiviral potential, proved by an in vitro or/and in vivo study, and possess therapeutic potential.

Conclusion: In this review article, we present an overview of the developments in the area of synthesis of compounds that contain quinoxaline scaffold with antitumor or antiviral activities.

Keywords: o-Phenylenediamine, Diketo acid, quinoxaline, antitumor activity, antiviral activity, benzodiazepene.

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Article Details

VOLUME: 15
ISSUE: 3
Year: 2018
Page: [220 - 226]
Pages: 7
DOI: 10.2174/1570193X14666171201143357
Price: $58

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