Biological Importance of Phenol Derivatives as Potent Bioactive Compound: A Review

Author(s): Arvind Kumar*, Arun K. Mishra.

Journal Name: Letters in Organic Chemistry

Volume 15 , Issue 4 , 2018

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Graphical Abstract:


Introduction: Phenol or carbolic acid is an aromatic compound and has mild acidic nature. In 1834, it was firstly achieved by Friedlieb Ferdinand by the destructive extraction of coal tar. It is used as a significant raw material in quite a lot of chemical manufacturing. Phenol derivatives have been found to possess Antimicrobial, Analgesic, Anti-inflammatory, Antioxidant, Anti-convulsant, Anti-cancer, Anesthetic, Antiseptic and Disinfecticides, Anti-tubercular and Anti-parkinson activity. Several more compounds have been discovered and many are still being focused.

Conclusion: The main objective of this article is to show up the different derivatives and the pharmacological activities of Phenol and its derivatives. It can be concluded that Phenol and its derivatives posses significant therapeutic functions and many potent derivatives are still to be discovered.

Keywords: Analgesic activity, anti-cancer activity, anti-convulsant activity, anti-inflammatory activity, anti-microbial activity, anti-oxidant activity, anti-tubercular activity, phenol.

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Article Details

Year: 2018
Page: [251 - 264]
Pages: 14
DOI: 10.2174/1570178614666171130155539
Price: $65

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