A simple, convenient and facile approach for the synthesis of a series of 2,3-
dihydroquinazolin-4(1H)-ones in an environmentally benign method has been developed. This method
involves a direct cyclocondensation of 2-aminobenzamide with aromatic aldehydes and ketones using
aspartic acid as a catalyst in water.
Keywords: Amino acid, catalyst, 2, 3-Dihydroquinazolin-4(1H)-ones, 2-aminobenzamide, ketones, water.
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