Natural Bioactive New Withanolides

(E-pub Ahead of Print)

Author(s): Qian-Qian Xu, Kui-Wu Wang*.

Journal Name: Mini-Reviews in Medicinal Chemistry

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Withanolides are a group of highly oxygenated steroids derived from a C28 ergostane skeleton, and have attracted significant scientific interest due to their complex structural features and multiple bioactivities. More than 170 new natural withanolides were isolated and identified in the last 5 years. This review provides a comprehensive summary of the structural, biological and pharmacological activities and distribution of these new compounds.

Keywords: Withanolide, Structure, Biological activities.

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(E-pub Ahead of Print)
DOI: 10.2174/1389557518666171129164056
Price: $95

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