Transformation Products of Pharmaceuticals in the Environment: Formation and Analysis

Author(s): Sandra Babic*, Martina Biosic, Irena Skoric.

Journal Name: Current Organic Chemistry

Volume 22 , Issue 10 , 2018

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Graphical Abstract:


Identification of transformation products and elucidation of degradation pathways of pharmaceuticals in the environment is a challenging task due to the numerous compounds, their low concentrations, and complexity of the environmental matrices. This manuscript summarizes present knowledge about main degradation routes of pharmaceuticals in the environment and review published methods and approaches for their determination in environmental samples, with a special emphasis on the mass spectrometry and nuclear magnetic resonance techniques.

Keywords: Pharmaceuticals, environment, fate, degradation path, liquid chromatography, mass spectrometry, nuclear magnetic resonance.

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Article Details

Year: 2018
Page: [987 - 1004]
Pages: 18
DOI: 10.2174/1385272822666171122160926
Price: $58

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PDF: 15