Identification of transformation products and elucidation of degradation pathways
of pharmaceuticals in the environment is a challenging task due to the numerous
compounds, their low concentrations, and complexity of the environmental matrices. This
manuscript summarizes present knowledge about main degradation routes of pharmaceuticals
in the environment and review published methods and approaches for their determination
in environmental samples, with a special emphasis on the mass spectrometry and nuclear
magnetic resonance techniques.
Keywords: Pharmaceuticals, environment, fate, degradation path, liquid chromatography, mass spectrometry, nuclear magnetic resonance.
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