Synthesis of Heterocycles by Using Propargyl Compounds as Versatile Synthons

Author(s): Ruimao Hua*, Tauqir A. Nizami.

Journal Name: Mini-Reviews in Organic Chemistry

Volume 15 , Issue 3 , 2018

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Abstract:

Background: Propargyl compounds such as propargyl alcohols and propargyl amines having several reactive centers have attracted a lot of attention for their various transformation. In particular, these compounds have been recently used as the versatile synthons in the synthesis of various heterocycles via their intramolecular cycloisomerization or cyclocondensation with other unsaturated compounds under different conditions.

Conclusion: In this mini-review paper, we focus on summarizing the recent advances in the synthesis of oxygen- and nitrogen-heterocycles by using propargyl alcohols, propargyl amines and their derivatives as one of reactants.

Keywords: Cyclization, heterocycles, propargyl alcohols, propargyl amines, versatile synthons, cyclocondensation.

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Article Details

VOLUME: 15
ISSUE: 3
Year: 2018
Page: [198 - 207]
Pages: 10
DOI: 10.2174/1570193X14666171114122235
Price: $58

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