Growth Kinetics and Oncologic Outcomes for Small Renal Masses Managed with Active Surveillance: A Review of the Literature

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Author(s): Benjamin T Ristau*, Thomas W Fuller, Ricardo Rios, Cristina Ho, Jeffrey J Tomaszewski.

Journal Name: Anti-Cancer Agents in Medicinal Chemistry
(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

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Abstract:

An increasing number of enhancing renal masses are being discovered incidentally on cross-sectional imaging. Many can be characterized as small renal masses (SRMs), the natural history of which is heterogeneous and poorly understood. Active surveillance has been proposed as an initial management strategy for these tumors, particularly in the old and infirmed patient population. Herein, a rigorous review of the literature is provided to explore the incidence and epidemiology of SRMs as well as the growth kinetics and oncologic outcomes of SRMs under observation. Special consideration is given to competing risks to mortality and costanalyses for the management of the SRM. Finally, the role of percutaneous biopsy and current prospective clinical trials of active surveillance for SRMs are reviewed.

Keywords: small renal mass, kidney cancer, active surveillance, outcomes, kidney biopsy, cost containment

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Article Details

(E-pub Ahead of Print)
DOI: 10.2174/1871520617666171114111053
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