Dendrimers: Nanosized Multifunctional Platform for Drug Delivery

Author(s): Ankur Vaidya*, Shweta Jain, Kamla Pathak, Devender Pathak.

Journal Name: Drug Delivery Letters

Volume 8 , Issue 1 , 2018

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Graphical Abstract:


Background: Dendrimers are nano-sized drug delivery systems that present significant advantages, including ease of construction, large number of polymers available for their synthesis and amenability to affix various types of ligands for targeting to specific site. The nanosystem with unique functional architecture and macromolecular characteristics has garnered considerable interest amongst researchers and various research reports and patents inputs can be found in literature.

Objective: Till date more than ten families of dendrimers have been reported for their wide applications in medicine including diagnostic/clinical, and also in industrial arenas. Unlike traditional polymers, many dendrimers have remarkable features like improved aqueous solubility, biocompatibility, polyvalency and precise molecular weight. These features make dendrimers an ideal vehicle for drug delivery and targeting applications.

Conclusion: The current review is an attempt to define types of dendrimers and their applications in drug delivery and cosmetics. The write up also highlights future perspectives of the multifunctional nanosystem.

Keywords: Dendrimers, applications, cosmetics, biomedical, pharmaceutical, nanosized multifunctional platform.

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Article Details

Year: 2018
Page: [3 - 19]
Pages: 17
DOI: 10.2174/2210303107666171109112523
Price: $25

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PDF: 61
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