In contemporary society, a large number of adults experience more or less decrease in bone mass or
bone density. It is known that bone, in response to mechanical loading, undergoes continuous remodeling
throughout life, which helps in the growth and maintenance of the skeleton. Since mechanical loading acts as an
important stimulus for bone growth and maintenance, it can be used as a strategy to prevent and treat the conditions
of bone loss. This review summarizes the current knowledge about the effects of mechanical loading on
bone, in the level of cells and tissue.
Keywords: Mechanical loading, bone, bone mass, bone density, osteocytes, osteoblasts, bone loss.
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