New Strategies for the Prevention and Treatment of Bone Loss - From Mechanical Loading Point of View

Author(s): Ce Shi , Bai Yang*, Hongchen Sun*.

Journal Name: Current Pharmaceutical Design

Volume 23 , Issue 41 , 2017

Abstract:

In contemporary society, a large number of adults experience more or less decrease in bone mass or bone density. It is known that bone, in response to mechanical loading, undergoes continuous remodeling throughout life, which helps in the growth and maintenance of the skeleton. Since mechanical loading acts as an important stimulus for bone growth and maintenance, it can be used as a strategy to prevent and treat the conditions of bone loss. This review summarizes the current knowledge about the effects of mechanical loading on bone, in the level of cells and tissue.

Keywords: Mechanical loading, bone, bone mass, bone density, osteocytes, osteoblasts, bone loss.

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Article Details

VOLUME: 23
ISSUE: 41
Year: 2017
Page: [6264 - 6271]
Pages: 8
DOI: 10.2174/1381612823666171108121350
Price: $58

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