Background: Due to significant biological activity associated with N-, O- and Sheterocycles,
a number of reports for their synthesis have appeared in recent decades. Traditional approaches
require expensive or highly specialized equipment or would be of limited use to the synthetic
organic chemist due to their highly inconvenient approaches. This review summarizes the applications
of gold catalysts with emphasis of their synthetic applications for nitrogen containing five-membered
Objective: The transition metal catalyzed protocols have attracted the attention as compared to other
synthetic methodologies because they use easily available substrates to build multiply substituted
complicated molecules directly under mild conditions. In organic synthesis one of the most powerful
and useful protocols are constituted by transition metal catalyzed coupling transformations. The
N-heterocycles are synthesized by this convenient and useful tool.
Conclusion: The efficient and chemoselective synthesis of heterocycles by this technique has appeared
as an important tool. This review shows a highly dynamic research field and the employment
of gold catalysts in organic synthesis. Several strategies have been pointed out in the past few years, to
meet more sustainable, efficient and environmentally benign chemical products and procedures. The
catalytic strategies have been focus of intense research because they avoid the use of toxic reagents.
Among these catalytic strategies, highly rewarding and an important method in heterocycles synthesis
is metal catalyzed synthesis.