Seizure control is a critical component of care in many neurosurgical conditions. The development of
seizures in patients without a previously identified seizure disorder occurs in a significant proportion of traumatic
brain injury, subarachnoid hemorrhage, and brain tumor patients. In this literature review and synthesis, we will
discuss the incidence of seizures in selected conditions, indications and evidence for the initiation of antiepileptic
drugs (AEDs), suggested duration of usage for AEDs, and current AED guidelines by the American Academy of
Neurology (AAN), Congress of Neurological Surgeons (CNS), American Academy of Neurological Surgeons
(AANS) and international committees.
Keywords: Prophylactic treatment, antiepileptic drugs, neurosurgical conditions, seizure control, seizure disorder, traumatic brain injury.
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