Knoevenagel Reaction Catalyzed by a Reusable Bronsted Acid Based on 1-Alkyl-1,2,4-triazolium Tetrafluoroborate

Title:Knoevenagel Reaction Catalyzed by a Reusable Bronsted Acid Based on 1-Alkyl-1,2,4-triazolium Tetrafluoroborate

Volume: 15 Issue: 2

Author(s): Elango Kandasamy*, Sankaranarayanan Nagarajan and Tanveer M. Shaikh*

Affiliation:

• Department of Sciences, Amrita School of Engineering Coimbatore, Amrita Vishwa Vidyapeetham, Amrita University, Coimbatore,India

• Department of Chemistry, CNCS, Mekelle University, Mekele,Ethiopia

Keywords: Aldehyde, benzylidenemalononitrile, Brønsted acid, ionic liquids, Knoevenagel reaction, reusable catalyst, triazolium salts.

Abstract: The Knoevenagel reaction is one of the most useful methods for the synthesis of α,β- unsaturated nitriles. We disclose an efficient protocol for the Knoevenagel reaction of aldehydes with malononitrile catalyzed by 1-alkyl-1,2,4-triazolium salts to afford the corresponding products in excellent yields. The important feature of this reaction is the catalyst; 1-alkyl-1,2,4-triazolium salts are recycled and reused. Furthermore, the reaction conditions are environment friendly and do not produce any hazardous waste.

Cite this article as:

Kandasamy Elango *, Nagarajan Sankaranarayanan and Shaikh M. Tanveer *, Knoevenagel Reaction Catalyzed by a Reusable Bronsted Acid Based on 1-Alkyl-1,2,4-triazolium Tetrafluoroborate, Letters in Organic Chemistry 2018; 15 (2) . https://dx.doi.org/10.2174/1570178614666171017164516