Knoevenagel Reaction Catalyzed by a Reusable Bronsted Acid Based on 1-Alkyl-1,2,4-triazolium Tetrafluoroborate

Author(s): Elango Kandasamy*, Sankaranarayanan Nagarajan, Tanveer M. Shaikh*.

Journal Name: Letters in Organic Chemistry

Volume 15 , Issue 2 , 2018

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Abstract:

The Knoevenagel reaction is one of the most useful methods for the synthesis of α,β- unsaturated nitriles. We disclose an efficient protocol for the Knoevenagel reaction of aldehydes with malononitrile catalyzed by 1-alkyl-1,2,4-triazolium salts to afford the corresponding products in excellent yields. The important feature of this reaction is the catalyst; 1-alkyl-1,2,4-triazolium salts are recycled and reused. Furthermore, the reaction conditions are environment friendly and do not produce any hazardous waste.

Keywords: Aldehyde, benzylidenemalononitrile, Brønsted acid, ionic liquids, Knoevenagel reaction, reusable catalyst, triazolium salts.

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Article Details

VOLUME: 15
ISSUE: 2
Year: 2018
Page: [133 - 138]
Pages: 6
DOI: 10.2174/1570178614666171017164516
Price: $65

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