Background: Neurodegenerative disorders are among the most common challenging
diseases that affect the population with extreme medical and financial burdens. Widely seen
neurodegeneration affects population of all ages, as it progresses with age, affecting a large
proportion of elderly population including patients, caregivers, and immensely increasing the
financial load of the country. These diseases have a very complex nature that frequently results
from combined genetic, environmental and pathological factors. Various challenges are faced
by the researchers working on the pathogenesis and the possible treatment of neurodegenerative
Objective: The review has analysed for recent patent documents and treatment approaches for
neurodegenerative disorders. This review does not relate to potential targets such as ( i.e. protein
where modulation could be predicted to impact on pathophysiology), rather it mainly focuses on
various available patented approaches for neurodegenerative disorders.
Method: The study design is based on updating the international and national literatures and an
exhaustive patent search, compiling various patented documents for the treatment of neurodegenerative
disorders (EP2282779A1, US20110229555A1) to provide information in the state
of technological innovation in terms of research and development.
Results: In the present review, the authors described various neurodegenerative diseases, there
treatment strategies and emphasized on various patented approaches for age-related neurodegenerative
disorders such as novel therapeutic methods for treating Alzheimer's and associated disorders
via modulated cell stress response EP2282779A1, through combined therapies that modulate
Conclusion: The review will attract the interest of academics, researchers, students and pharmaceutical
companies with regard to the recent on-going activities in neurodegenerative disorders.