Background: Endoscopic Ultrasound has been used in the clinical arena for almost 35
years and it is now well-integrated in everyday hospital practice.
Method: We conducted a systematic review of the available English-language articles.
Objective: The purpose of this review is to summarize all the relevant indications to endoscopic ultrasound
and analyze its relevant data in terms of accuracy and clinical outcomes.
Results: More than 5000 scientific papers published in the literature have demonstrated its high accuracy
for the diagnosis and staging of a variety of benign and malignant conditions. Staging indications
include gastroesophageal and rectal cancers. Diagnostic, staging and therapeutic indications include
diseases of the pancreaticobiliary area. Finally, differential diagnosis of submucosal tumors represents
another important indication to this technique.
Keywords: Endoscopic Ultrasound, esophageal cancer, EUS, fine needle aspiration, gastric cancer, pancreatic cancer, submucosal
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