Frontiers in Biomaterials

Frontiers in Biomaterials

Volume: 4

Biomaterials for Tissue Engineering

This volume reviews the published knowledge about bioactive composites, protein scaffolds and hydrogels. Chapters also detail the production parameters and clarify the evaluation protocol for ...
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Hydrogels: Types, Structure, Properties, and Applications

Pp. 143-169 (27)

Amirsalar Khandan, Hossein Jazayeri, Mina D. Fahmy and Mehdi Razavi

Abstract

Hydrogels are one of the important biomaterials for tissue engineering applications. The hydrogel scaffolds’ state-of-the-art properties for clinical applications are subject to on-going researches. Hydrogels, such as hybrid and protein-based ones, contain protein domains. Hydrogels show unique advantages compared to other polymeric materials; which made them applicable as periodontal materials and drug carriers, as well as bone matrices. The first description of its use was developed by a Scottish chemist, Thomas Graham, as a solid, jelly-like material that can have different physical and mechanical properties. Gels are defined as a substantially dilute crosslinked system, which doesn’t have flow in the steady-state. Gels can be typically characterized as liquids, while they behave like solids due to a 3D cross-linked network within the liquid. The gels’ IUPAC definition classifies them as a non-fluid polymer network that is expanded throughout its whole volume by a fluid. Thus, this chapter aims to describe the composition, synthesis techniques, and applications of hydrogel scaffolds for biomedical approaches.

Keywords:

Biotechnology, Hydrogel, Nanomaterials, Polymers, Scaffolds, Tissue Engineering.

Affiliation:

Young Researchers and Elite Club, Khomeinishahr Branch, Islamic Azad University, Isfahan, Iran.