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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Review Article

Recent Advances in the Application of the Heck Reaction in the Synthesis of Heterocyclic Compounds: An Update

Author(s): Majid M. Heravi*, Razieh Moradi* and Masoumeh Malmir

Volume 22, Issue 2, 2018

Page: [165 - 198] Pages: 34

DOI: 10.2174/1385272821666171002121126

Price: $65

Abstract

Background: The reaction of aryl halides or vinyl halides with activated alkenes in the presence of Palladium-catalyst along with a base for the formation of the C-C bond is called the Heck reaction. This reaction has been employed extensively in the synthesis of heterocyclic compounds.

Methodology: We have highlighted these applications in 2010.

Conclusion: This review aims to cover the recent application of the Heck reaction in the synthesis of heterocyclic compounds during a period from 2010 to 2017.

Keywords: Heck reaction, heterocyclic compounds, Pd, palladium, carbon-carbon bond formation, catalysis.

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