Asthma is an inflammatory disease which affects millions of people worldwide. Therefore,
it is necessary to search for new sources of therapies for the treatment of these patients in order to improve
their quality of life. From content analysis of literature of new therapeutic targets, there are various
targets and drugs reported to be promising for the treatment of asthma. Interleukins involved in inflammatory
processes are often presented as candidate targets for new drugs. The action of such therapeutics
would not only affect interleukins, but also their receptors. Small molecules (e.g. ligustrazine
and SP600125) and large molecule antibodies (e.g. lebrikizumab, benralizumab, dupilumab) are being
considered as novel agents for the pharmacotherapy of asthma. Therefore, through this research, we
can see advances in the search for new targets and promising drugs to treat asthma. It is expected that
these new drug candidates will eventually be approved and marketed so that asthma patients can use
them to enhance their quality of life.
Keywords: Asthma, drugs, monoclonal antibody, natural products, targets, therapeutic targets.
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