Statins in Peripheral Arterial Disease

Author(s): Scott T. Chiesa, Nikos Papageorgiou, Marietta Charakida*.

Journal Name: Current Pharmaceutical Design

Volume 23 , Issue 46 , 2017

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Abstract:

Peripheral arterial disease (PAD) is a common atherosclertico condition affecting the lower extremities. PAD patients share similar cardiovascular risk factors to coronary artery disease patients and suffer from increased cardiovascular morbidity and mortality. Statins have been widely used in coronary artery disease patients but have been underused in patients with PAD. In the current review, we present data which support the beneficial role of statins in both reducing cardiovascular events and improving symptom-related outcomes in PAD patients. Alongside their lipid lowering effects, their pleiotropic actions are also discussed. Recent guidelines, which strongly recommend the administration of statins in PAD patients, are also presented.

Keywords: Statins, outcomes, peripheral arterial disease, pleiotropic effects, atherosclertico condition.

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Article Details

VOLUME: 23
ISSUE: 46
Year: 2017
Page: [7099 - 7108]
Pages: 10
DOI: 10.2174/1381612823666170926130826
Price: $58

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