Generic placeholder image

Current Nutrition & Food Science

Editor-in-Chief

ISSN (Print): 1573-4013
ISSN (Online): 2212-3881

Research Article

Manufacture of the Functional Noodle and its Effects on Postprandial 2h-blood Glucose and Serum Lipid Levels of Subjects with IGT

Author(s): Yong-Taek Kim*, Zong-Do Jo, Hung-Mun Pang, Chan-Ok Paek and Chang-Sok Mun

Volume 16, Issue 4, 2020

Page: [625 - 630] Pages: 6

DOI: 10.2174/1573401313666170920154311

Price: $65

Abstract

Background: The earliest determinant of progression to type 2 diabetes is a loss of early insulin secretion, a defect which results in postprandial hyperglycemia and is often believed to reflect insulin resistance. In Asian countries including our country, noodle is the traditional food which has been eaten from ancient times and is taken one or two times a day. The functional noodle is a staple meeting nutritional requirements for the prevention and treatment of Impaired Glucose Tolerance (IGT).

Methods: FNs were prepared using the noodle making machine according to Barak et al. with slight modifications. After giving FNs prepared by three mixing ratios of main materials to the IGT-induced rats for 30 days, the levels of postprandial 2h-blood glucose in all experimental groups and control group were measured to determinate the optimal mixing ratio of FN. After the IGT subjects in experimental group ate 200g of FN (dried weight) in exchange for a lunch for 60 days, the levels of postprandial 2h-blood glucose and of TG and TC in serum were measured to compare with that in the control group who had not undergone control in their diet.

Result: After 30 days of experiment, the levels of postprandial 2h-blood glucose in rats of pl group 4 were lowest. The levels of postprandial 2h-blood glucose in the control group that most of them had not undergone control in their diet were increased, but that in experimental group who had taken FN decreased from 30 days of experiment to be significantly different after 60 days. The concentrations of serum TC and TG of IGT subjects in the experimental group were decreased compared with that in the control group, but significance among two groups was achieved only in the concentration of serum TC.

Conclusion: FN made in the 4:3:3 ratio of powder of corn, powder of bean cake defatted and powder of peeled whole potato is more effective to decrease the levels of postprandial 2h-blood glucose. FN is a staple type of functional food that could be used for the treatment of IGT.

Keywords: IGT, noodle, postprandial 2h-blood glucose, total cholesterol (TC), triglyceride (TG), type 2 diabetes.

« Previous
Graphical Abstract
[1]
Sato T. Glycemic effects of solanine in rats. Jpn J Pharmacol 1967; 17(4): 652-8.
[http://dx.doi.org/10.1254/jjp.17.652] [PMID: 4385229]
[2]
Mitrakou A, Kelley D, Mokan M, et al. Role of reduced suppression of glucose production and diminished early insulin release in impaired glucose tolerance. N Engl J Med 1992; 326(1): 22-9.
[http://dx.doi.org/10.1056/NEJM199201023260104] [PMID: 1727062]
[3]
World Health Organization, prevention of diabetes mellitus.Report of WHO study group, WHO Technical Report Series. 844 Geneva: World Health Organization 1994; 1-100.
[4]
Pascale RW, Wing RR, Butler BA, Mullen M, Bononi P. Effects of a behavioral weight loss program stressing calorie restriction versus calorie plus fat restriction in obese individuals with NIDDM or a family history of diabetes. Diabetes Care 1995; 18(9): 1241-8.
[http://dx.doi.org/10.2337/diacare.18.9.1241] [PMID: 8612437]
[5]
Reavan GM. Banting lecture 1998: Role of insulin resistance in human disease. Diabetes 1998; 37(12): 1595-607.
[6]
American Diabetes Association. Nutrition recommendations and principles for people with diabetes mellitus (Position Statement). Diabetes Care 1999; 22(Suppl. 1): S42.
[7]
Tominaga M, Eguchi H, Manaka H, Igarashi K, Kato T, Sekikawa A. Impaired glucose tolerance is a risk factor for cardiovascular disease, but not impaired fasting glucose. The Funagata Diabetes Study. Diabetes Care 1999; 22(6): 920-4.
[http://dx.doi.org/10.2337/diacare.22.6.920] [PMID: 10372242]
[8]
Diplock AT, Aggett PJ, Ashwell M, et al. Scientific concepts of functional foods in Europe. Consensus document. Br J Nutr 1999; 81(Suppl. 1): S1-S27.
[http://dx.doi.org/10.1017/S0007114599000471] [PMID: 10999022]
[9]
DECODE Study Group, the European Diabetes Epidemiology Group.. Glucose tolerance and cardiovascular mortality: comparison of fasting and 2-hour diagnostic criteria. Arch Intern Med 2001; 161(3): 397-405.
[http://dx.doi.org/10.1001/archinte.161.3.397] [PMID: 11176766]
[10]
Friedman M, Roitman JN, Kozukue N. Glycoalkaloid and calystegine contents of eight potato cultivars. J Agric Food Chem 2003; 51(10): 2964-73.
[http://dx.doi.org/10.1021/jf021146f] [PMID: 12720378]
[11]
Winzell MS, Ahrén B. The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes. Diabetes 2004; 53(Suppl. 3): S215-9.
[http://dx.doi.org/10.2337/diabetes.53.suppl_3.S215] [PMID: 15561913]
[12]
Julia RP. Krause’s Food, Nutrition, & Diet Therapy Medicine & Health Science Book. USA: WB Saunders 2006.
[13]
Kao TH, Chen BH. Functional components in soybean cake and their effects on antioxidant activity. J Agric Food Chem 2006; 54(20): 7544-55.
[http://dx.doi.org/10.1021/jf061586x] [PMID: 17002420]
[14]
Gao D, Li Q, Liu Z, et al. Hypoglycemic effects and mechanisms of action of Cortex Lycii Radicis on alloxan-induced diabetic mice. Yakugaku Zasshi 2007; 127(10): 1715-21.
[http://dx.doi.org/10.1248/yakushi.127.1715] [PMID: 17917429]
[15]
Govindarajan R, Asare-Anane H, Persaud S, Jones P, Houghton PJ. Effect of Desmodium gangeticum extract on blood glucose in rats and on insulin secretion in vitro. Planta Med 2007; 73(5): 427-32.
[http://dx.doi.org/10.1055/s-2007-967176] [PMID: 17431824]
[16]
Passmore R. Human nutrition and dietetics. Churchill Livingstone: Edinburgh, New York 1984.

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy